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UID:20250711T175319EDT-6567plRZBu@132.216.98.100
DTSTAMP:20250711T215319Z
DESCRIPTION:The rules by which human cells\, tissues and organs are specifi
 ed and built during development are still largely unknown. In my talk I wi
 ll describe how we have begun to fill this gap by using single cell and sp
 atial genomics technologies on embryonic/foetal material. Our cross-organ 
 single cell and spatial atlas of immune cells\, which also incorporates pa
 ired BCR\, αβTCR\, and γδTCR datasets\, provides a detailed characterisati
 on of generic and tissue-specific properties of developing immunity. Our h
 igh-resolution atlas of human limb development at multiple timepoints allo
 ws us to define major lineages and cell types\, delineate the stepwise pro
 gramme of transcription factors governing cell fate\, and determine the co
 nservation of insights from mouse models. Human developmental processes\, 
 whether in systems distributed across many organs (as in immunity) or in c
 omplex multi-tissue structures (as in the limb)\, are thus increasingly tr
 actable using single cell techniques.\n\nThis seminar will be given online
  via Zoom. Details in attached poster.\n
DTSTART:20220121T160000Z
DTEND:20220121T170000Z
SUMMARY:Online seminar: Deciphering Human Development and Disease One Cell 
 at a Time
URL:/physiology/channels/event/online-seminar-decipher
 ing-human-development-and-disease-one-cell-time-336050
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